Clinical investigators are currently exploring ustekinumab, an IL-12 and IL-23 antagonist, for graft vs host disease (GVHD) prophylaxis in matched unrelated donor hematopoietic cell transplantation (HCT) recipients. A phase 2 …
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GVHD
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Bone marrow transplantion
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Bone marrow transplantion
Long-term survival outcomes of allo-HCT in AML with fludarabine/melphalan conditioning and tacrolimus/sirolimus GVHD prophylaxis
by Dongyun Yangby Dongyun YangRussell NH, Hills RK, Thomas A, Thomas I, Kjeldsen L, Dennis M, et al. Outcomes of older patients aged 60 to 70 years undergoing reduced intensity transplant for acute myeloblastic …
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Bone marrow transplantion
‘I can’t remember the last time I saw someone with bad gut GVHD’: BMT expert reflects on recent lifesaving successes
by News Sourceby News SourceFred Hutch Cancer Center opened its doors 50 years ago, founded by the team that made bone marrow transplantation a reality. Since the breakthroughs in the late 1960s that showed the Nobel …
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Bone marrow transplantion
ATG or post-transplant cyclophosphamide to prevent GVHD in matched unrelated stem cell transplants?
Patient characteristics Baseline characteristics of the study population are shown in Table 1. A total of 8,764 patients were included, of whom 7,725 (88%) received his rATG and 1,039 (12%) …