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Clinical investigators are currently exploring ustekinumab, an IL-12 and IL-23 antagonist, for graft vs host disease (GVHD) prophylaxis in matched unrelated donor hematopoietic cell transplantation (HCT) recipients. A phase 2 …

At the American Society of Nephrology Kidney Week 2025, late-breaking results from the phase 2 BESTOW trial offered updates in transplant immunosuppression. The study evaluated tegoprubart, an investigational anti-CD40L monoclonal …

Eledon Pharmaceuticals (ELDN) just shared results from its Phase 2 BESTOW trial on tegoprubart for kidney transplant rejection. While the main goal was not fully met, the data points to …

Mohammed Al-Oweib, Director of the Planning Department at the Therapeutic Services Support and Development Agency, announced that an agreement has been reached to launch the first phase of the bone …

An im­mune an­ti­body-cleav­ing drug from Hansa Bio­phar­ma could soon make it eas­i­er for some pa­tients to get kid­ney trans­plants in the US. The Swedish biotech … Sign up to read …

Biogen Inc. Global Phase 3 Overlap Study Evaluates the Efficacy and Safety of Ferzaltamab compared to placebo in adults with delayed AMR AMR is the main cause of kidney transplant …

Introduction Kidney transplantation is considered as the optimal treatment option for end-stage kidney disease. It enables greater longevity and better quality of life compared to peritoneal dialysis and hemodialysis (1, …

82% (n=9/11) of patients who received felzaltamab experienced resolution of symptoms. Antibody-mediated rejection The proportion of patients meeting the Banff criteria in the 24-week biopsy was significantly increased compared to …

Competing interests GMC serves on the board of directors of Satellite Healthcare, a not-for-profit dialysis provider. His institution (Stanford University) has received grant funding from clinical trial sponsor CSL Behring. …

TFF Pharma Co., Ltd. Oral Presentation Presenting Latest Data from a Phase 2 Study Demonstrating Successful Transition of Patients from Oral Tacrolimus to TFF TAC FORT WORTH, Texas, March 25, …