Clinical investigators are currently exploring ustekinumab, an IL-12 and IL-23 antagonist, for graft vs host disease (GVHD) prophylaxis in matched unrelated donor hematopoietic cell transplantation (HCT) recipients. A phase 2 …
Tag:
prophylaxis
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Bone marrow transplantion
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Bone marrow transplantion
Long-term survival outcomes of allo-HCT in AML with fludarabine/melphalan conditioning and tacrolimus/sirolimus GVHD prophylaxis
by Dongyun Yangby Dongyun YangRussell NH, Hills RK, Thomas A, Thomas I, Kjeldsen L, Dennis M, et al. Outcomes of older patients aged 60 to 70 years undergoing reduced intensity transplant for acute myeloblastic …
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Bone marrow transplantion
Compound staphylococcal lysostaphin for oral mucositis prophylaxis in hematopoietic stem cell transplantation recipients: a non-inferiority randomized trial
by Zhengwen Panby Zhengwen PanElad S, Yarom N, Zadik Y, Kuten-Shorrer M, Sonis ST. The broadening scope of oral mucositis and oral ulcerative mucosal toxicities of anticancer therapies. CA Cancer J Clin. 2022;72:57–77. PubMed …
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Bone marrow transplantion
Impact of graft CD34+ cell count on hematologic recovery in patients receiving post-transplant cyclophosphamide prophylaxis
by Wenhui Gaoby Wenhui GaoGooptu M, Romee R, St Martin A, Arora M, Al Malki M, Antin JH, et al. HLA haploidentical versus matched unrelated donor transplantation with post-transplant cyclophosphamide-based prophylaxis. Blood. 2021;138:273–82. https://doi.org/10.1182/blood.2021011281. …