Home Kidney TransplantationThe Scottish team has received the International Award for groundbreaking bedside tests, aiming to tackle transplant rejection

The Scottish team has received the International Award for groundbreaking bedside tests, aiming to tackle transplant rejection

by Amy
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A pioneering team of kidney researchers at Scotland, supported by Kidney Research UK and Stoneygate Trust, became the first British winner of the American Transplant Association's Transplant Fantasy Association, and became the challenge for the job to develop tests that would help detect rejection of kidney transplants faster, faster and cheaper.

The team based at the University of Edinburgh and the University of Glasgow, led by Stephen Knight, a senior specialist registrar for kidney transplantation, has developed a simple urine test that can detect biomarkers released during kidney transplant rejection, called Granzyme B. The team received a £40,000 emerging grant from Kidney Research UK, jointly funded by Stoneygate Trust to help develop and test rapid tests.

New tests can lead to faster treatments

The test occurs in just 2 hours and is designed to be done at the bedside, so doctors can monitor the condition of the kidneys that have been implanted, quickly assess whether the patient's anti-rejection medication is working, and may limit the need for a painful biopsy. So far, the tests have been consistently performed in exams. Approximately 100 patients, and It may lead to faster treatments that will help prevent rejection of transplants

The team's work is now recognized on the international stage, and their projects are the first outside North America to win the challenge of ported fantasy. After beating participants across North America and taking the five finalist list, the team traveled to Arizona to present the lawsuit to a panel of experts at the association's cutting-edge 2025 conference. They were voted as winners by representatives of the conference.

Although transplants are often the best option for better quality and quantity for patients whose kidneys have stopped working effectively, approximately 10-15% of patients experience rejection within the first year of receiving the transplant.*. While early detection is important to ensure best results, the standard way to check whether rejection is occurring is kidney biopsy – an invasive procedure that involves removing tissue samples from the implanted kidney. This procedure can be painful, risky and time-consuming to process.

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